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Chemical structure of SAR7334

GC33424

SAR7334

Also known as 4-[[(1R,2R)-2-[(3R)-3-aminopiperidin-1-yl]-2,3-dihydro-1H-inden-1-yl]oxy]-3-chlorobenzonitrile

SAR7334 is a potent and specific TRPC6 inhibitor, inhibiting TRPC6 currents with IC50 of 7·9 nM

ChemicalCAS1333210-07-3MW367.87FormulaC21H22ClN3O
CAS number
1333210-07-3
Molecular weight
367.87
Formula
C21H22ClN3O
Solubility
DMSO : ≥ 370 mg/mL (1005·79 mM)
InChIKey
RLKRLNQEXBPQGQ-OZOXKJRCSA-N
Catalogue number
GC33424
Brand
GLPBIO
Computed properties PubChem CID 53378752 · XLogP 3.5 · TPSA 62.3 Ų · H-bond donors 1
XLogP
3.5
TPSA
62.3 Ų
H-bond donors
1
H-bond acceptors
4
Rotatable bonds
3
Heavy atoms
26

SMILES C1C[C@H](CN(C1)[C@@H]2CC3=CC=CC=C3[C@H]2OC4=C(C=C(C=C4)C#N)Cl)N

Computed descriptors from PubChem (CID 53378752), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.