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Chemical structure of POT-4

GC63151

POT-4

Also known as 2-[(4R,7S,10S,13S,19S,22S,25S,28S,31S,34R)-34-[[(2S,3S)-2-acetamido-3-methylpentanoyl]amino]-4-[[(2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl]carbamoyl]-25-(3-amino-3-oxopropyl)-7-(3-carbamimidamidopropyl)-10-(1H-imidazol-4-ylmethyl)-19-(1H-indol-3-ylmethyl)-13-methyl-28-[(1-methylindol-3-yl)methyl]-6,9,12,15,18,21,24,27,30,33-decaoxo-31-propan-2-yl-1,2-dithia-5,8,11,14,17,20,23,26,29,32-decazacyclopentatriacont-22-yl]acetic acid

POT-4 (AL-78898A), a Compstatin derivative, is a potent inhibitor of complement factor C3 activation

ChemicalCAS934461-40-2MW1627.85FormulaC72H102N22O18S2
CAS number
934461-40-2
Molecular weight
1627.85
Formula
C72H102N22O18S2
Solubility
DMSO ： 100 mg/mL (61·43 mM; Need ultrasonic); H2O ： 50 mg/mL (30·72 mM; Need ultrasonic)
InChIKey
WMEMLXDTLKSUOD-OGCOPIPOSA-N
Catalogue number
GC63151
Brand
GLPBIO
Computed properties PubChem CID 16158103 · XLogP -2.9 · TPSA 684 Ų · H-bond donors 22
XLogP
-2.9
TPSA
684 Ų
H-bond donors
22
H-bond acceptors
22
Rotatable bonds
26
Heavy atoms
114

SMILES CC[C@H](C)[C@@H](C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)C(C)C)CC2=CN(C3=CC=CC=C32)C)CCC(=O)N)CC(=O)O)CC4=CNC5=CC=CC=C54)C)CC6=CNC=N6)CCCNC(=N)N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N)NC(=O)C

Computed descriptors from PubChem (CID 16158103), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.