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Chemical structure of POSH-IN-2

GC75825

POSH-IN-2

Also known as (E)-3-pyridin-3-yl-1-[4-[(E)-3-pyridin-3-ylprop-2-enoyl]phenyl]prop-2-en-1-one

POSH-IN-2 (MIDI), a mitochondrial division inhibitor, is a DRP1 inhibitor that potently blocks mitochondrial fragmentation induced by cellular stresses and genetic mitochondrial lesions

ChemicalCAS348145-43-7MW340.37FormulaC22H16N2O2
CAS number
348145-43-7
Molecular weight
340.37
Formula
C22H16N2O2
Solubility
DMSO： 5 mg/mL (14·69 mM; ultrasonic and warming and adjust pH to 2 with TFA and heat to 60°C)
InChIKey
IOESTAVFGVAMRH-YDWXAUTNSA-N
Catalogue number
GC75825
Brand
GLPBIO
Computed properties PubChem CID 5333035 · XLogP 3.3 · TPSA 59.9 Ų · H-bond donors 0
XLogP
3.3
TPSA
59.9 Ų
H-bond donors
0
H-bond acceptors
4
Rotatable bonds
6
Heavy atoms
26

SMILES C1=CC(=CN=C1)/C=C/C(=O)C2=CC=C(C=C2)C(=O)/C=C/C3=CN=CC=C3

Computed descriptors from PubChem (CID 5333035), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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