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Chemical structure of NV-5138

GC63121

NV-5138

Also known as (2S)-2-amino-5,5-difluoro-4,4-dimethylpentanoic acid

NV-5138, a leucine analog, is the first selective and orally active brain mTORC1 activator, binding to Sestrin2

ChemicalCAS2095886-80-7MW181.18FormulaC7H13F2NO2
CAS number
2095886-80-7
Molecular weight
181.18
Formula
C7H13F2NO2
Solubility
DMSO : 10 mg/mL (55·19 mM; Need ultrasonic)
InChIKey
HRFIMCJTDKEPPV-BYPYZUCNSA-N
Catalogue number
GC63121
Brand
GLPBIO
Computed properties PubChem CID 129050791 · XLogP -1 · TPSA 63.3 Ų · H-bond donors 2
XLogP
-1
TPSA
63.3 Ų
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
4
Heavy atoms
12

SMILES CC(C)(C[C@@H](C(=O)O)N)C(F)F

Computed descriptors from PubChem (CID 129050791), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.