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Chemical structure of HTL14242

GC63008

HTL14242

Also known as 3-chloro-5-[6-(5-fluoro-2-pyridinyl)pyrimidin-4-yl]benzonitrile

HTL14242 (HTL0014242) is an advanced and orally active mGlu5 NAM with a pKi?and a pIC50 of 9·3 and 9·2, respectively

ChemicalCAS1644645-32-8MW310.71FormulaC16H8ClFN4
CAS number
1644645-32-8
Molecular weight
310.71
Formula
C16H8ClFN4
Solubility
DMSO ： 12·5 mg/mL (40·23 mM; Need ultrasonic)
InChIKey
FQAXDSVNYVVQSE-UHFFFAOYSA-N
Catalogue number
GC63008
Brand
GLPBIO
Computed properties PubChem CID 86763358 · XLogP 2.9 · TPSA 62.5 Ų · H-bond donors 0
XLogP
2.9
TPSA
62.5 Ų
H-bond donors
0
H-bond acceptors
5
Rotatable bonds
2
Heavy atoms
22

SMILES C1=CC(=NC=C1F)C2=CC(=NC=N2)C3=CC(=CC(=C3)C#N)Cl

Computed descriptors from PubChem (CID 86763358), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.