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Chemical structure of HTLV-1 Tax (11-19)

GA22933

HTLV-1 Tax (11-19)

Also known as (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-3-phenylpropanoyl]amino]acetyl]amino]-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoic acid

Human T lymphotropic virus type 1 HTLV-1 Tax (11-19) is an immunodominant HLA-A2-restricted epitope· It is recognized by a high number of CD8? cytotoxic T lymphocytes (CTLs) in patients with HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), a demyelinating inflammatory neurologic disease associated with HTLV-1 infection·H-6096 therefore represents a useful tool to elucidate the role of antigen-specific CD8? CTLs in HAM/TSP

ChemicalCAS141677-18-1MW1070.3FormulaC56H79N9O12
CAS number
141677-18-1
Molecular weight
1070.3
Formula
C56H79N9O12
Solubility
Soluble in DMSO
InChIKey
BUTXAHWFQUYLDT-JAOFDYSYSA-N
Catalogue number
GA22933
Brand
GLPBIO
Computed properties PubChem CID 444317 · XLogP 3.2 · TPSA 328 Ų · H-bond donors 11
XLogP
3.2
TPSA
328 Ų
H-bond donors
11
H-bond acceptors
13
Rotatable bonds
28
Heavy atoms
77

SMILES CC(C)C[C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NCC(=O)N[C@@H](CC2=CC=C(C=C2)O)C(=O)N3CCC[C@H]3C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC4=CC=C(C=C4)O)C(=O)N[C@@H](C(C)C)C(=O)O)N

Computed descriptors from PubChem (CID 444317), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Documents
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