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Chemical structure of FR901464

GC62978

FR901464

Also known as [(E,2S)-5-[[(2R,5S,6S)-6-[(2E,4E)-5-[(4R,5R,7S)-4,7-dihydroxy-7-methyl-1,6-dioxaspiro[2.5]octan-5-yl]-3-methylpenta-2,4-dienyl]-2,5-dimethyloxan-3-yl]amino]-5-oxopent-3-en-2-yl] acetate

FR901464 is a potent spliceosome inhibitor with prominent anti-tumor and anti-cancer effects

ChemicalCAS146478-72-0MW507.62FormulaC27H41NO8
CAS number
146478-72-0
Molecular weight
507.62
Formula
C27H41NO8
Solubility
DMSO ： 100 mg/mL (197·00 mM; Need ultrasonic)
InChIKey
PJKVJJDQXZARCA-AYSBKWRUSA-N
Catalogue number
GC62978
Brand
GLPBIO
Computed properties PubChem CID 6448738 · XLogP 2 · TPSA 127 Ų · H-bond donors 3
XLogP
2
TPSA
127 Ų
H-bond donors
3
H-bond acceptors
8
Rotatable bonds
9
Heavy atoms
36

SMILES C[C@H]1CC([C@H](O[C@H]1C/C=C(\C)/C=C/[C@@H]2[C@H](C3(C[C@@](O2)(C)O)CO3)O)C)NC(=O)/C=C/[C@H](C)OC(=O)C

Computed descriptors from PubChem (CID 6448738), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.