Loading...
Chemical structure of EST73502 hydrochloride

GC62960

EST73502 hydrochloride

Also known as (2R)-9-[2-(2,5-difluorophenyl)ethyl]-4-ethyl-2-methyl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one;hydrochloride

EST73502 hydrochloride is a selective, orally active and blood-brain barrier (BBB) penetrant dual μ-opioid receptor (MOR) agonist and σ1 receptor (σ1R) antagonist, with Kis of 64 nM and 118 nM for MOR and σ1R, respectively

ChemicalCAS2535970-65-9MW388.88FormulaC19H27ClF2N2O2
CAS number
2535970-65-9
Molecular weight
388.88
Formula
C19H27ClF2N2O2
Solubility
DMSO ： 50 mg/mL (128·57 mM; Need ultrasonic)
InChIKey
WZJJIHSIBMZUIN-PFEQFJNWSA-N
Catalogue number
GC62960
Brand
GLPBIO
Computed properties PubChem CID 153535293 · TPSA 32.8 Ų · H-bond donors 1 · H-bond acceptors 5
TPSA
32.8 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
4
Heavy atoms
26

SMILES CCN1CC2(CCN(CC2)CCC3=C(C=CC(=C3)F)F)O[C@@H](C1=O)C.Cl

Computed descriptors from PubChem (CID 153535293), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.