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Chemical structure of AMPA receptor modulator-2

GC62840

AMPA receptor modulator-2

Also known as 6-[2,5-bis(trifluoromethyl)imidazo[4,5-b]pyridin-3-yl]-3H-1,3-benzothiazol-2-one

AMPA receptor modulator-2 (Example 134) is a AMPA receptor modulator, with a pIC50 of 10·1 for TARPγ2 dependent AMPA receptor

ChemicalCAS2034181-36-5MW404.29FormulaC15H6F6N4OS
CAS number
2034181-36-5
Molecular weight
404.29
Formula
C15H6F6N4OS
Solubility
DMSO : 250 mg/mL (618·37 mM; Need ultrasonic)|Water : < 0·1 mg/mL (insoluble)
InChIKey
BPZAQDCXSKBMKM-UHFFFAOYSA-N
Catalogue number
GC62840
Brand
GLPBIO
Computed properties PubChem CID 122654476 · XLogP 4 · TPSA 85.1 Ų · H-bond donors 1
XLogP
4
TPSA
85.1 Ų
H-bond donors
1
H-bond acceptors
10
Rotatable bonds
1
Heavy atoms
27

SMILES C1=CC2=C(C=C1N3C4=C(C=CC(=N4)C(F)(F)F)N=C3C(F)(F)F)SC(=O)N2

Computed descriptors from PubChem (CID 122654476), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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