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Chemical structure of ALK4290

GC62833

ALK4290

Also known as 2-[[(2R)-1-[1-[(4-chloro-3-methylphenyl)methyl]piperidin-4-yl]-5-oxopyrrolidine-2-carbonyl]amino]-N,N,6-trimethylpyridine-4-carboxamide

ALK4290 (AKST4290) is a potent and orally actively CCR3 inhibitor extracted from patent US20130261153A1, compound Example 2, with a Ki of 3·2 nM for hCCR3

ChemicalCAS1251528-23-0MW512.04FormulaC27H34ClN5O3
CAS number
1251528-23-0
Molecular weight
512.04
Formula
C27H34ClN5O3
Solubility
DMSO ： 50 mg/mL (97·65 mM; ultrasonic and warming and heat to 60°C)
InChIKey
DWKNOLCXIFYNFV-HSZRJFAPSA-N
Catalogue number
GC62833
Brand
GLPBIO
Computed properties PubChem CID 59534386 · XLogP 2.9 · TPSA 85.9 Ų · H-bond donors 1
XLogP
2.9
TPSA
85.9 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
6
Heavy atoms
36

SMILES CC1=CC(=CC(=N1)NC(=O)[C@H]2CCC(=O)N2C3CCN(CC3)CC4=CC(=C(C=C4)Cl)C)C(=O)N(C)C

Computed descriptors from PubChem (CID 59534386), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.