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Chemical structure of AAK1-IN-1

GC62822

AAK1-IN-1

Also known as (2S)-1-[[2-(difluoromethyl)-6-[2-(difluoromethyl)-4-pyridinyl]-3-pyridinyl]oxy]-2,4-dimethylpentan-2-amine

AAK1-IN-1 (LX-9211) is a highly selective, brain-penetrant, potent AAK1 (adaptor associated kinase 1) inhibitor with an IC50 of 2 nM

ChemicalCAS1815613-42-3MW385.4FormulaC19H23F4N3O
CAS number
1815613-42-3
Molecular weight
385.4
Formula
C19H23F4N3O
Solubility
DMSO ： 220 mg/mL (570·84 mM; Need ultrasonic)
InChIKey
RKAHOQATMSONTM-IBGZPJMESA-N
Catalogue number
GC62822
Brand
GLPBIO
Computed properties PubChem CID 118419773 · XLogP 3.7 · TPSA 61 Ų · H-bond donors 1
XLogP
3.7
TPSA
61 Ų
H-bond donors
1
H-bond acceptors
8
Rotatable bonds
8
Heavy atoms
27

SMILES CC(C)C[C@@](C)(COC1=C(N=C(C=C1)C2=CC(=NC=C2)C(F)F)C(F)F)N

Computed descriptors from PubChem (CID 118419773), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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