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Chemical structure of AAT-008

GC42666

AAT-008

Also known as 4-[(1S)-1-[[5-chloro-2-(3-fluorophenoxy)pyridine-3-carbonyl]amino]ethyl]benzoic acid

AAT-008 is an orally bioavailable and potent antagonist of the prostaglandin E2 (PGE2) receptor subtype 4 (EP4; IC50 = 16·3 nM in a human EP4 functional assay)

ChemicalCAS847727-81-5MW414.8FormulaC21H16ClFN2O4
CAS number
847727-81-5
Molecular weight
414.8
Formula
C21H16ClFN2O4
Solubility
DMF： 30 mg/ml,DMSO： 30 mg/ml,Ethanol： 0·5 mg/ml
InChIKey
FKXDPPYCCKCVCW-LBPRGKRZSA-N
Catalogue number
GC42666
Brand
GLPBIO
Computed properties PubChem CID 11577792 · XLogP 4.1 · TPSA 88.5 Ų · H-bond donors 2
XLogP
4.1
TPSA
88.5 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
6
Heavy atoms
29

SMILES C[C@@H](C1=CC=C(C=C1)C(=O)O)NC(=O)C2=C(N=CC(=C2)Cl)OC3=CC(=CC=C3)F

Computed descriptors from PubChem (CID 11577792), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.