GC62716
MD-222
MD-222 is the first-in-class highly potent PROTAC degrader of MDM2· MD-222 consists of ligands for Cereblon and MDM2· MD-222 induces rapid degradation of the MDM2 protein and activation of wild-type p53 in cells· MD-222 has anticancer effects
ChemicalCAS2136246-72-3MW893.83FormulaC48H47Cl2FN6O6
- CAS number
- 2136246-72-3
- Molecular weight
- 893.83
- Formula
- C48H47Cl2FN6O6
- Solubility
- DMSO ： 200 mg/mL (223·76 mM; Need ultrasonic)
- InChIKey
- RRSNDVCODIMOFX-MPKOGUQCSA-N
- Catalogue number
- GC62716
- Brand
- GLPBIO
Computed properties PubChem CID 131988640 · XLogP 6.4 · TPSA 166 Ų · H-bond donors 5
- XLogP
- 6.4
- TPSA
- 166 Ų
- H-bond donors
- 5
- H-bond acceptors
- 8
- Rotatable bonds
- 11
- Heavy atoms
- 63
SMILES C1CCC2(CC1)[C@@]3([C@H]([C@@H](N2)C(=O)NC4=CC=C(C=C4)C(=O)NCCCCCC5=C6CN(C(=O)C6=CC=C5)C7CCC(=O)NC7=O)C8=C(C(=CC=C8)Cl)F)C9=C(C=C(C=C9)Cl)NC3=O
Computed descriptors from PubChem (CID 131988640), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il