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Chemical structure of OP-5244

GC62694

OP-5244

Also known as [(2R)-2-[[(2R,3S,4R,5R)-5-[6-chloro-4-(cyclopentylamino)pyrazolo[3,4-d]pyrimidin-1-yl]-3,4-dihydroxyoxolan-2-yl]methoxy]-1-hydroxy-3-methoxypropan-2-yl]phosphonic acid

OP-5244 is a potent and orally active inhibitor of CD73, with an IC50 of 0·25 nM

ChemicalCAS2381268-71-7MW537.89FormulaC19H29ClN5O9P
CAS number
2381268-71-7
Molecular weight
537.89
Formula
C19H29ClN5O9P
Solubility
DMSO ： 250 mg/mL (464·78 mM; Need ultrasonic)
InChIKey
BQCRMLSBGAKPFW-RTPDKIPNSA-N
Catalogue number
GC62694
Brand
GLPBIO
Computed properties PubChem CID 154585769 · XLogP -1.6 · TPSA 202 Ų · H-bond donors 6
XLogP
-1.6
TPSA
202 Ų
H-bond donors
6
H-bond acceptors
13
Rotatable bonds
10
Heavy atoms
35

SMILES COC[C@](CO)(OC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C3=NC(=NC(=C3C=N2)NC4CCCC4)Cl)O)O)P(=O)(O)O

Computed descriptors from PubChem (CID 154585769), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.