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Chemical structure of Icerguastat

GC62677

Icerguastat

Also known as 2-[(E)-(2-chlorophenyl)methylideneamino]guanidine

Icerguastat (Sephin1), a derivative of Guanabenz lacking the α2-adrenergic activity, is a selective inhibitor of the phosphatase regulatory subunit PPP1R15A (R15A)

ChemicalCAS951441-04-6MW196.64FormulaC8H9ClN4
CAS number
951441-04-6
Molecular weight
196.64
Formula
C8H9ClN4
Solubility
DMSO ： 250 mg/mL (1271·36 mM; Need ultrasonic)
InChIKey
PDWJALXSRRSUHR-LFYBBSHMSA-N
Catalogue number
GC62677
Brand
GLPBIO
Computed properties PubChem CID 9561611 · XLogP 1.1 · TPSA 76.8 Ų · H-bond donors 2
XLogP
1.1
TPSA
76.8 Ų
H-bond donors
2
H-bond acceptors
2
Rotatable bonds
2
Heavy atoms
13

SMILES C1=CC=C(C(=C1)/C=N/N=C(N)N)Cl

Computed descriptors from PubChem (CID 9561611), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.