GC62615
AS-99
Also known as N-[[3-(3-carbamothioylphenyl)-1-[1-(trifluoromethylsulfonyl)piperidin-4-yl]indol-6-yl]methyl]-1-methylazetidine-3-carboxamide
AS-99 is a first-in-class, potent and selective ASH1L histone methyltransferase inhibitor (IC50=0·79μM, Kd=0·89μM) with anti-leukemic activity· AS-99 blocks cell proliferation, induces apoptosis and differentiation, downregulates MLL fusion target genes, and reduces the leukemia burden in vivo
ChemicalCAS2323623-93-2MW593.68FormulaC27H30F3N5O3S2
- CAS number
- 2323623-93-2
- Molecular weight
- 593.68
- Formula
- C27H30F3N5O3S2
- InChIKey
- VPQCHIWQHIOPQS-UHFFFAOYSA-N
- Catalogue number
- GC62615
- Brand
- GLPBIO
Computed properties PubChem CID 138630366 · XLogP 2.9 · TPSA 141 Ų · H-bond donors 2
- XLogP
- 2.9
- TPSA
- 141 Ų
- H-bond donors
- 2
- H-bond acceptors
- 9
- Rotatable bonds
- 7
- Heavy atoms
- 40
SMILES CN1CC(C1)C(=O)NCC2=CC3=C(C=C2)C(=CN3C4CCN(CC4)S(=O)(=O)C(F)(F)F)C5=CC(=CC=C5)C(=S)N
Computed descriptors from PubChem (CID 138630366), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il