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Chemical structure of AS-99 TFA

GC62849

AS-99 TFA

AS-99 TFA is a first-in-class, potent and selective ASH1L histone methyltransferase inhibitor (IC50=?0·79??M, Kd=?0·89??M) with anti-leukemic activity· AS-99 TFA blocks cell proliferation, induces apoptosis and differentiation, downregulates MLL fusion target genes, and reduces the leukemia burden in vivo

ChemicalMW707.71FormulaC29H31F6N5O5S2
CAS number
Molecular weight
707.71
Formula
C29H31F6N5O5S2
Solubility
DMSO : 250 mg/mL (353·25 mM; Need ultrasonic)
Catalogue number
GC62849
Brand
GLPBIO

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.