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Chemical structure of Syk-IN-4

GC62592

Syk-IN-4

Also known as 5-[[4-[4-[(dimethylamino)methyl]-3-methylpyrazol-1-yl]pyrimidin-2-yl]amino]-N,1-dimethylindazole-3-carboxamide

Syk-IN-4 is a potent, selective and orally bioavailable SYK inhibitor with an IC50 of 0·31 nM

ChemicalCAS2932264-95-2MW419.48FormulaC21H25N9O
CAS number
2932264-95-2
Molecular weight
419.48
Formula
C21H25N9O
Solubility
DMSO ： 62·5 mg/mL (148·99 mM; Need ultrasonic)
InChIKey
IXNQUCOVJRJRGJ-UHFFFAOYSA-N
Catalogue number
GC62592
Brand
GLPBIO
Computed properties PubChem CID 154573768 · XLogP 1.9 · TPSA 106 Ų · H-bond donors 2
XLogP
1.9
TPSA
106 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
6
Heavy atoms
31

SMILES CC1=NN(C=C1CN(C)C)C2=NC(=NC=C2)NC3=CC4=C(C=C3)N(N=C4C(=O)NC)C

Computed descriptors from PubChem (CID 154573768), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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