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Chemical structure of Syk-IN-1

GC61942

Syk-IN-1

Also known as 3-[[(1R,2S)-2-aminocyclohexyl]amino]-5-(1H-indol-7-ylamino)-1,2,4-triazine-6-carboxamide

Syk-IN-1 (compound 4) is a potent Syk inhibitor, with an IC50 of 35 nM

ChemicalCAS1491150-77-6MW366.42FormulaC18H22N8O
CAS number
1491150-77-6
Molecular weight
366.42
Formula
C18H22N8O
Solubility
DMSO ： 100 mg/mL (272·91 mM)
InChIKey
FPQNRXITKTZFMF-NWDGAFQWSA-N
Catalogue number
GC61942
Brand
GLPBIO
Computed properties PubChem CID 72202597 · XLogP 1.7 · TPSA 148 Ų · H-bond donors 5
XLogP
1.7
TPSA
148 Ų
H-bond donors
5
H-bond acceptors
7
Rotatable bonds
5
Heavy atoms
27

SMILES C1CC[C@H]([C@H](C1)N)NC2=NC(=C(N=N2)C(=O)N)NC3=CC=CC4=C3NC=C4

Computed descriptors from PubChem (CID 72202597), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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