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Chemical structure of Enpatoran

GC62489

Enpatoran

Also known as 5-[(3R,5S)-3-amino-5-(trifluoromethyl)piperidin-1-yl]quinoline-8-carbonitrile

Enpatoran (M5049) is a potent, orally active and dual TLR7/8 inhibitor with IC50s of 11·1 nM and 24·1 nM in HEK293 cells, respectively

ChemicalCAS2101938-42-3MW320.31FormulaC16H15F3N4
CAS number
2101938-42-3
Molecular weight
320.31
Formula
C16H15F3N4
Solubility
DMSO ： 24·44 mg/mL (76·30 mM; Need ultrasonic)
InChIKey
BJXYHBKEQFQVES-NWDGAFQWSA-N
Catalogue number
GC62489
Brand
GLPBIO
Computed properties PubChem CID 129240620 · XLogP 2.7 · TPSA 65.9 Ų · H-bond donors 1
XLogP
2.7
TPSA
65.9 Ų
H-bond donors
1
H-bond acceptors
7
Rotatable bonds
1
Heavy atoms
23

SMILES C1[C@@H](CN(C[C@@H]1N)C2=C3C=CC=NC3=C(C=C2)C#N)C(F)(F)F

Computed descriptors from PubChem (CID 129240620), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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