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Chemical structure of Enpatoran hydrochloride

GC62471

Enpatoran hydrochloride

Also known as 5-[(3R,5S)-3-amino-5-(trifluoromethyl)piperidin-1-yl]quinoline-8-carbonitrile;hydrochloride

Enpatoran (M5049) hydrochloride is a potent, orally active and dual TLR7/8 inhibitor with IC50s of 11·1 nM and 24·1 nM in HEK293 cells, respectively

ChemicalCAS2101945-93-9MW356.77FormulaC16H16ClF3N4
CAS number
2101945-93-9
Molecular weight
356.77
Formula
C16H16ClF3N4
Solubility
DMSO ： 16·67 mg/mL (46·72 mM; ultrasonic and warming and heat to 60°C)
InChIKey
OHYZGHQWGHDMRP-ZVWHLABXSA-N
Catalogue number
GC62471
Brand
GLPBIO
Computed properties PubChem CID 129241087 · TPSA 65.9 Ų · H-bond donors 2 · H-bond acceptors 7
TPSA
65.9 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
1
Heavy atoms
24

SMILES C1[C@@H](CN(C[C@@H]1N)C2=C3C=CC=NC3=C(C=C2)C#N)C(F)(F)F.Cl

Computed descriptors from PubChem (CID 129241087), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
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