Loading...
Chemical structure of TH1338

GC62474

TH1338

Also known as (19S)-21-amino-10,19-diethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione

TH1338 (compound 3b), an orally active camptothecin derivative and a potent chemotherapeutic agent for cancer, demonstrates excellent cytotoxic potency against human tumor cell lines in vitro· TH1338 (compound 3b) possesses significant brain penetration, favorable efflux pump properties, and hematological toxicity profile

ChemicalCAS1258494-60-8MW391.42FormulaC22H21N3O4
CAS number
1258494-60-8
Molecular weight
391.42
Formula
C22H21N3O4
Solubility
DMSO ： 10 mg/mL (25·55 mM; Need ultrasonic)
InChIKey
GDSWDKUWTYXXOX-QFIPXVFZSA-N
Catalogue number
GC62474
Brand
GLPBIO
Computed properties PubChem CID 53318291 · XLogP 0.8 · TPSA 106 Ų · H-bond donors 2
XLogP
0.8
TPSA
106 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
2
Heavy atoms
29

SMILES CCC1=C2CN3C(=C(C4=C(C3=O)COC(=O)[C@@]4(CC)O)N)C2=NC5=CC=CC=C51

Computed descriptors from PubChem (CID 53318291), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.