Loading...
Chemical structure of TH1760

GB40387

TH1760

Also known as 6-[4-(1H-indole-5-carbonyl)piperazin-1-yl]sulfonyl-3H-1,3-benzoxazol-2-one

TH1760 is a first-in-class, potent, selective and cell-active NUDT15 (MTH2) inhibitor with an IC50 value of 25 nM

ChemicalCAS2567914-01-4MW426.45FormulaC20H18N4O5S
CAS number
2567914-01-4
Molecular weight
426.45
Formula
C20H18N4O5S
InChIKey
HNCVDRFFJZJQRW-UHFFFAOYSA-N
Catalogue number
GB40387
Brand
GLPBIO
Computed properties PubChem CID 146048072 · XLogP 1.3 · TPSA 120 Ų · H-bond donors 2
XLogP
1.3
TPSA
120 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
3
Heavy atoms
30

SMILES C1CN(CCN1C(=O)C2=CC3=C(C=C2)NC=C3)S(=O)(=O)C4=CC5=C(C=C4)NC(=O)O5

Computed descriptors from PubChem (CID 146048072), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.