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Chemical structure of RIPK3-IN-1

GC62455

RIPK3-IN-1

Also known as N-[4-[[2-(cyclopropanecarbonylamino)-4-pyridinyl]oxy]-2,3-dimethylphenyl]-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide

RIPK3-IN-1 is a RIPK3 type II DFG-out inhibitor with an IC50 of 9·1 nM

ChemicalCAS2361139-70-8MW512.53FormulaC29H25FN4O4
CAS number
2361139-70-8
Molecular weight
512.53
Formula
C29H25FN4O4
Solubility
DMSO ： 5 mg/mL (9·76 mM; ultrasonic and warming and heat to 80°C)
InChIKey
PETCZXAONWLUFT-UHFFFAOYSA-N
Catalogue number
GC62455
Brand
GLPBIO
Computed properties PubChem CID 138393291 · XLogP 4.2 · TPSA 101 Ų · H-bond donors 2
XLogP
4.2
TPSA
101 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
7
Heavy atoms
38

SMILES CC1=C(C=CC(=C1C)OC2=CC(=NC=C2)NC(=O)C3CC3)NC(=O)C4=CC=CN(C4=O)C5=CC=C(C=C5)F

Computed descriptors from PubChem (CID 138393291), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.