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Chemical structure of IMT1B

GC62446

IMT1B

Also known as (3S)-1-[(2R)-2-[4-(2-chloro-4-fluorophenyl)-2-oxochromen-7-yl]oxypropanoyl]piperidine-3-carboxylic acid

IMT1B (LDC203974) is an orally active, noncompetitive and specific allosteric inhibitor of mitochondrial RNA polymerase (POLRMT) and inhibits mitochondrial DNA (mtDNA) expression· IMT1B has anti-tumour effects

ChemicalCAS2304621-06-3MW473.88FormulaC24H21ClFNO6
CAS number
2304621-06-3
Molecular weight
473.88
Formula
C24H21ClFNO6
Solubility
DMSO ： 250 mg/mL (527·56 mM; Need ultrasonic)
InChIKey
PFEKWBKJUBCXDT-KGLIPLIRSA-N
Catalogue number
GC62446
Brand
GLPBIO
Computed properties PubChem CID 138490769 · XLogP 3.7 · TPSA 93.1 Ų · H-bond donors 1
XLogP
3.7
TPSA
93.1 Ų
H-bond donors
1
H-bond acceptors
7
Rotatable bonds
5
Heavy atoms
33

SMILES C[C@H](C(=O)N1CCC[C@@H](C1)C(=O)O)OC2=CC3=C(C=C2)C(=CC(=O)O3)C4=C(C=C(C=C4)F)Cl

Computed descriptors from PubChem (CID 138490769), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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