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Chemical structure of IMR-1A

GC36304

IMR-1A

Also known as 2-[2-methoxy-4-[(E)-(4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]phenoxy]acetic acid

IMR-1A, a acid metabolite of IMR-1, is a Notch inhibitor with an IC50 of 0·5 μM· IMR-1A has a 50-fold increase in potency with respect to IMR-1· IMR-1 can metabolize in vivo to IMR-1A

ChemicalCAS331862-41-0MW325.36FormulaC13H11NO5S2
CAS number
331862-41-0
Molecular weight
325.36
Formula
C13H11NO5S2
Solubility
DMSO： 2 mg/mL (6·15 mM); Water： ＜ 0·1 mg/mL (insoluble)
InChIKey
DVBJNSKWHSGTDK-BJMVGYQFSA-N
Catalogue number
GC36304
Brand
GLPBIO
Computed properties PubChem CID 1354721 · XLogP 2.3 · TPSA 142 Ų · H-bond donors 2
XLogP
2.3
TPSA
142 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
5
Heavy atoms
21

SMILES COC1=C(C=CC(=C1)/C=C/2\C(=O)NC(=S)S2)OCC(=O)O

Computed descriptors from PubChem (CID 1354721), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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