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Chemical structure of CK2 inhibitor 2

GC62337

CK2 inhibitor 2

Also known as 5-(3-chloroanilino)-N-(2-hydroxyethyl)benzo[c][2,6]naphthyridine-8-carboxamide

CK2 inhibitor 2 is a potent, selective and orally active inhibitor of CK2, with an IC50 of 0·66 nM· CK2 inhibitor 2 shows high selectivity for Clk2 (IC50=32·69 nM)/CK2· CK2 inhibitor 2 exhibits favorable antiproliferative and antitumor activity

ChemicalCAS2641079-92-5MW392.84FormulaC21H17ClN4O2
CAS number
2641079-92-5
Molecular weight
392.84
Formula
C21H17ClN4O2
Solubility
DMSO : 50 mg/mL (127·28 mM; ultrasonic and warming and heat to 60°C)
InChIKey
FPWXVWZFQXQWTH-UHFFFAOYSA-N
Catalogue number
GC62337
Brand
GLPBIO
Computed properties PubChem CID 156621381 · XLogP 3.5 · TPSA 87.1 Ų · H-bond donors 3
XLogP
3.5
TPSA
87.1 Ų
H-bond donors
3
H-bond acceptors
5
Rotatable bonds
5
Heavy atoms
28

SMILES C1=CC(=CC(=C1)Cl)NC2=NC3=C(C=CC(=C3)C(=O)NCCO)C4=C2C=CN=C4

Computed descriptors from PubChem (CID 156621381), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.