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Chemical structure of NCGC00378430

GC62286

NCGC00378430

Also known as N-(4-methoxy-3-morpholin-4-ylsulfonylphenyl)-3-pyrrol-1-ylbenzamide

NCGC00378430 is a potent SIX1/EYA2 interaction inhibitor· NCGC00378430 partially reverses transcriptional and metabolic profiles mediated by SIX1 overexpression and reverses SIX1-induced TGF-β signaling and epithelial-mesenchymal transition (EMT)· NCGC00378430 inhibits SIX1-mediated breast cancer metastasis in a mouse model

ChemicalCAS920650-00-6MW441.5FormulaC22H23N3O5S
CAS number
920650-00-6
Molecular weight
441.5
Formula
C22H23N3O5S
Solubility
DMSO ： 100 mg/mL (226·50 mM; Need ultrasonic)
InChIKey
IFXCVBOQNYHBMX-UHFFFAOYSA-N
Catalogue number
GC62286
Brand
GLPBIO
Computed properties PubChem CID 16361161 · XLogP 1.9 · TPSA 98.3 Ų · H-bond donors 1
XLogP
1.9
TPSA
98.3 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
6
Heavy atoms
31

SMILES COC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)N3C=CC=C3)S(=O)(=O)N4CCOCC4

Computed descriptors from PubChem (CID 16361161), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.