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Chemical structure of NCGC00379308

GC19543

NCGC00379308

Also known as N-(1-phenylethyl)-2-piperazin-1-ylquinazolin-4-amine

NCGC00379308 is a positive allosteric modulator for thyrotropin receptor (TSHR), which initiates translocation of β-Arr 1 by direct TSHR activation and potentiates TSH-mediated preosteoblast differentiation in vitro

ChemicalCAS662164-09-2MW333.439FormulaC20H23N5
CAS number
662164-09-2
Molecular weight
333.439
Formula
C20H23N5
Solubility
DMSO : ≥ 125 mg/mL (374·89 mM)
InChIKey
LOGWGZNWEWFTJV-UHFFFAOYSA-N
Catalogue number
GC19543
Brand
GLPBIO
Computed properties PubChem CID 2950121 · XLogP 3.6 · TPSA 53.1 Ų · H-bond donors 2
XLogP
3.6
TPSA
53.1 Ų
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
4
Heavy atoms
25

SMILES CC(C1=CC=CC=C1)NC2=NC(=NC3=CC=CC=C32)N4CCNCC4

Computed descriptors from PubChem (CID 2950121), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.