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Chemical structure of Zanvipixant

GC62284

Zanvipixant

Also listed as JNJ-55308942

JNJ-55308942 is a high-affinity, selective, brain-penetrant P2X7 functional antagonist (hP2X7: IC50=10 nM, Ki=7·1 nM; rP2X7: IC50=15 nM, Ki=2·9 nM)

ChemicalCAS2166558-11-6MW425.32FormulaC17H12F5N7O
CAS number
2166558-11-6
Molecular weight
425.32
Formula
C17H12F5N7O
Solubility
DMSO : 250 mg/mL (587·79 mM; Need ultrasonic)
InChIKey
LMDWZBQISRTEBH-QMMMGPOBSA-N
Catalogue number
GC62284
Brand
GLPBIO
Computed properties PubChem CID 90408860 · XLogP 1.5 · TPSA 89.7 Ų · H-bond donors 0
XLogP
1.5
TPSA
89.7 Ų
H-bond donors
0
H-bond acceptors
11
Rotatable bonds
2
Heavy atoms
30

SMILES C[C@H]1CC2=C(CN1C(=O)C3=C(C(=NC=C3)C(F)(F)F)F)N=NN2C4=NC=C(C=N4)F

Computed descriptors from PubChem (CID 90408860), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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