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Chemical structure of CPL304110

GC62274

CPL304110

Also known as 2-[5-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]-6-(4-methylpiperazin-1-yl)-1H-benzimidazole

CPL304110 is a potent, orally active and selective inhibitor of fibroblast growth factor receptors FGFR (1-3), with IC50 values of 0·75 nM, 0·5 nM, and 3·05 nM for FGFR (1-3), respectively

ChemicalCAS1627826-19-0MW446.54FormulaC25H30N6O2
CAS number
1627826-19-0
Molecular weight
446.54
Formula
C25H30N6O2
Solubility
DMSO ： 100 mg/mL (223·94 mM; Need ultrasonic)
InChIKey
QHCGPJPIPKDWAT-UHFFFAOYSA-N
Catalogue number
GC62274
Brand
GLPBIO
Computed properties PubChem CID 136387462 · XLogP 3.6 · TPSA 82.3 Ų · H-bond donors 2
XLogP
3.6
TPSA
82.3 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
7
Heavy atoms
33

SMILES CN1CCN(CC1)C2=CC3=C(C=C2)N=C(N3)C4=NNC(=C4)CCC5=CC(=CC(=C5)OC)OC

Computed descriptors from PubChem (CID 136387462), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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