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Chemical structure of CPI-455 HCl

GC25305

CPI-455 HCl

Also known as 7-oxo-5-phenyl-6-propan-2-yl-1H-pyrazolo[1,5-a]pyrimidine-3-carbonitrile;hydrochloride

CPI-455 HCl is a specific KDM5 inhibitor with a half-maximal inhibitory concentration (IC50) of 10 ± 1 nM for full-length KDM5A in enzymatic assays, elevating global levels of H3K4 trimethylation (H3K4me3) and decreased the number of DTPs in multiple cancer cell line models treated with standard chemotherapy or targeted agents·This product has poor solubility, animal experiments are available, cell experiments please choose carefully!

ChemicalCAS2095432-28-1MW314.77FormulaC16H15ClN4O
CAS number
2095432-28-1
Molecular weight
314.77
Formula
C16H15ClN4O
Solubility
DMSO： Insoluble;Water： Insoluble;Ethanol： Insoluble
InChIKey
SNODPNXOTKXHHH-UHFFFAOYSA-N
Catalogue number
GC25305
Brand
GLPBIO
Computed properties PubChem CID 129896721 · TPSA 68.5 Ų · H-bond donors 2 · H-bond acceptors 4
TPSA
68.5 Ų
H-bond donors
2
H-bond acceptors
4
Rotatable bonds
2
Heavy atoms
22

SMILES CC(C)C1=C(N=C2C(=CNN2C1=O)C#N)C3=CC=CC=C3.Cl

Computed descriptors from PubChem (CID 129896721), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.