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Chemical structure of ERK-IN-3

GC62229

ERK-IN-3

Also known as N-[(1S)-2-amino-1-(3-chloro-5-fluorophenyl)ethyl]-1-[5-methyl-2-(oxan-4-ylamino)pyrimidin-4-yl]imidazole-4-carboxamide

ERK-IN-3 is a potent and orally active inhibitor of ERK· ERK-IN-3 inhibits ERK1/2 with low single-digit nM IC50 values· ERK-IN-3 can be used for the research of cancers driven by RAS mutations

ChemicalCAS2055597-12-9MW473.93FormulaC22H25ClFN7O2
CAS number
2055597-12-9
Molecular weight
473.93
Formula
C22H25ClFN7O2
Solubility
DMSO ： 250 mg/mL (527·50 mM; Need ultrasonic)
InChIKey
PWHIUQBBGPGFFV-GOSISDBHSA-N
Catalogue number
GC62229
Brand
GLPBIO
Computed properties PubChem CID 124122366 · XLogP 2.3 · TPSA 120 Ų · H-bond donors 3
XLogP
2.3
TPSA
120 Ų
H-bond donors
3
H-bond acceptors
8
Rotatable bonds
7
Heavy atoms
33

SMILES CC1=CN=C(N=C1N2C=C(N=C2)C(=O)N[C@H](CN)C3=CC(=CC(=C3)Cl)F)NC4CCOCC4

Computed descriptors from PubChem (CID 124122366), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.