Loading...
Chemical structure of CRBN modulator-1

GC62218

CRBN modulator-1

Also known as 2-(2,6-dioxopiperidin-3-yl)-5-hydroxybenzo[de]isoquinoline-1,3-dione

CRBN modulator-1, a Thalidomide analog and a CRBN modulator extracted from WO2020006262A1, compound 10, has an IC50 of 3·5 μM and a Ki of 0·98 μM

ChemicalCAS2407829-65-4MW324.29FormulaC17H12N2O5
CAS number
2407829-65-4
Molecular weight
324.29
Formula
C17H12N2O5
Solubility
DMSO ： 10 mg/mL (30·84 mM; ultrasonic and adjust pH to 2 with HCl)
InChIKey
WGTKYDFLBDSIPX-UHFFFAOYSA-N
Catalogue number
GC62218
Brand
GLPBIO
Computed properties PubChem CID 152258126 · XLogP 1 · TPSA 104 Ų · H-bond donors 2
XLogP
1
TPSA
104 Ų
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
1
Heavy atoms
24

SMILES C1CC(=O)NC(=O)C1N2C(=O)C3=CC=CC4=CC(=CC(=C43)C2=O)O

Computed descriptors from PubChem (CID 152258126), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.