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Chemical structure of CRBN-6-5-5-VHL

GC50619

CRBN-6-5-5-VHL

Also known as (2S,4R)-1-[(2S)-2-[5-[5-[6-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]hexoxy]pentoxy]pentanoylamino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide

Potent and selective cereblon degrader; cell-permeable

ChemicalCAS2362575-45-7MW972.21FormulaC51H69N7O10S
CAS number
2362575-45-7
Molecular weight
972.21
Formula
C51H69N7O10S
Solubility
Soluble in DMSO
InChIKey
LIMCHOLAKDUZDS-XARBDFOFSA-N
Catalogue number
GC50619
Brand
GLPBIO
Computed properties PubChem CID 145874883 · XLogP 5.6 · TPSA 254 Ų · H-bond donors 5
XLogP
5.6
TPSA
254 Ų
H-bond donors
5
H-bond acceptors
13
Rotatable bonds
27
Heavy atoms
69

SMILES CC1=C(SC=N1)C2=CC=C(C=C2)CNC(=O)[C@@H]3C[C@H](CN3C(=O)[C@H](C(C)(C)C)NC(=O)CCCCOCCCCCOCCCCCCNC4=CC=CC5=C4C(=O)N(C5=O)C6CCC(=O)NC6=O)O

Computed descriptors from PubChem (CID 145874883), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.