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Chemical structure of WH-4-025

GC62142

WH-4-025

Also known as [2-methyl-5-[[3-(trifluoromethyl)phenyl]carbamoyl]phenyl] N-(2,4-dimethoxyphenyl)-N-[2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]carbamate

WH-4-025 is a Salt-inducible kinase (SIK) inhibitor (WO2016023014 A2)

ChemicalCAS1876463-35-2MW741.76FormulaC39H38F3N7O5
CAS number
1876463-35-2
Molecular weight
741.76
Formula
C39H38F3N7O5
Solubility
DMSO ： 125 mg/mL (168·52 mM; Need ultrasonic)
InChIKey
MWWDOHSKUDECFQ-UHFFFAOYSA-N
Catalogue number
GC62142
Brand
GLPBIO
Computed properties PubChem CID 73707529 · XLogP 7.3 · TPSA 121 Ų · H-bond donors 2
XLogP
7.3
TPSA
121 Ų
H-bond donors
2
H-bond acceptors
13
Rotatable bonds
11
Heavy atoms
54

SMILES CC1=C(C=C(C=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)OC(=O)N(C3=C(C=C(C=C3)OC)OC)C4=NC(=NC=C4)NC5=CC=C(C=C5)N6CCN(CC6)C

Computed descriptors from PubChem (CID 73707529), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.