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Chemical structure of WIN 18446

GC10438

WIN 18446

Also known as 2,2-dichloro-N-[8-[(2,2-dichloroacetyl)amino]octyl]acetamide

WIN 18446 (Fertilysin) is a potent inhibitor of aldehyde dehydrogenase 1A2 (ALDH1A2) enzyme with an IC50 value of 0·3μM

ChemicalCAS1477-57-2MW366.11FormulaC12H20Cl4N2O2
CAS number
1477-57-2
Molecular weight
366.11
Formula
C12H20Cl4N2O2
Solubility
≥ 11·4mg/mL in DMSO
InChIKey
FAOMZVDZARKPFJ-UHFFFAOYSA-N
Catalogue number
GC10438
Brand
GLPBIO
Computed properties PubChem CID 15134 · XLogP 4.1 · TPSA 58.2 Ų · H-bond donors 2
XLogP
4.1
TPSA
58.2 Ų
H-bond donors
2
H-bond acceptors
2
Rotatable bonds
11
Heavy atoms
20

SMILES C(CCCCNC(=O)C(Cl)Cl)CCCNC(=O)C(Cl)Cl

Computed descriptors from PubChem (CID 15134), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Documents
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