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Chemical structure of JNJ-63576253

GC62106

JNJ-63576253

JNJ-63576253 (TRC-253) is a potent and orally active full antagonist of androgen receptor (AR), with IC50s of 37 and 54 nM for F877L mutant AR and wild-type AR in LNCaP cells· JNJ-63576253 can be used for the research of castration-resistant prostate cancer (CRPC)

ChemicalCAS2110428-64-1MW538.97FormulaC23H22ClF3N6O2S
CAS number
2110428-64-1
Molecular weight
538.97
Formula
C23H22ClF3N6O2S
Solubility
DMSO : 250 mg/mL (463·85 mM; Need ultrasonic)
Catalogue number
GC62106
Brand
GLPBIO

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.