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Chemical structure of LP-261

GC62092

LP-261

Also known as N-[3-(1H-indol-4-yl)-5-(2-methoxypyridine-4-carbonyl)phenyl]methanesulfonamide

LP-261 is a potent and orally active anti-mitotic agent and shows an inhibition of in vitro tubulin polymerization with an EC50 of 3·2 μM· LP-261 inhibits growth of a human non-small-cell lung tumor (NCI-H522) in vivo and can be used for cancer research

ChemicalCAS915412-67-8MW421.47FormulaC22H19N3O4S
CAS number
915412-67-8
Molecular weight
421.47
Formula
C22H19N3O4S
Solubility
DMSO : 33·33 mg/mL (79·08 mM)
InChIKey
YUVDELGTFILMBB-UHFFFAOYSA-N
Catalogue number
GC62092
Brand
GLPBIO
Computed properties PubChem CID 15603282 · XLogP 3.2 · TPSA 110 Ų · H-bond donors 2
XLogP
3.2
TPSA
110 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
6
Heavy atoms
30

SMILES COC1=NC=CC(=C1)C(=O)C2=CC(=CC(=C2)C3=C4C=CNC4=CC=C3)NS(=O)(=O)C

Computed descriptors from PubChem (CID 15603282), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.