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Chemical structure of Fmoc-Gly-Gly-Phe-OH

GC61416

Fmoc-Gly-Gly-Phe-OH

Also known as (2S)-2-[[2-[[2-(9H-fluoren-9-ylmethoxycarbonylamino)acetyl]amino]acetyl]amino]-3-phenylpropanoic acid

Fmoc-Gly-Gly-Phe-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)

ChemicalCAS160036-44-2MW501.53FormulaC28H27N3O6
CAS number
160036-44-2
Molecular weight
501.53
Formula
C28H27N3O6
InChIKey
UFGUUZVZUIXKQZ-DEOSSOPVSA-N
Catalogue number
GC61416
Brand
GLPBIO
Computed properties PubChem CID 14598599 · XLogP 3.3 · TPSA 134 Ų · H-bond donors 4
XLogP
3.3
TPSA
134 Ų
H-bond donors
4
H-bond acceptors
6
Rotatable bonds
11
Heavy atoms
37

SMILES C1=CC=C(C=C1)C[C@@H](C(=O)O)NC(=O)CNC(=O)CNC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24

Computed descriptors from PubChem (CID 14598599), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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