GC61211
PROTAC BET Degrader-10
Also known as 6-[[2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetyl]amino]-N-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]methyl]hexanamide
PROTAC BET Degrader-10 is a potent BET protein BRD4 degrader extracted from patent WO2017007612A1, example 37, connected by ligands for Cereblon and BRD4, with a DC50 of 49 nM
ChemicalCAS1957234-97-7MW783.29FormulaC39H39ClN8O6S
- CAS number
- 1957234-97-7
- Molecular weight
- 783.29
- Formula
- C39H39ClN8O6S
- InChIKey
- KVKRYCAWRGWYNN-MBMZGMDYSA-N
- Catalogue number
- GC61211
- Brand
- GLPBIO
Computed properties PubChem CID 124190914 · XLogP 3.3 · TPSA 213 Ų · H-bond donors 3
- XLogP
- 3.3
- TPSA
- 213 Ų
- H-bond donors
- 3
- H-bond acceptors
- 10
- Rotatable bonds
- 12
- Heavy atoms
- 55
SMILES CC1=C(SC2=C1C(=N[C@H](C3=NN=C(N32)C)CC(=O)NCCCCCC(=O)NCC4=C5C(=CC=C4)C(=O)N(C5=O)C6CCC(=O)NC6=O)C7=CC=C(C=C7)Cl)C
Computed descriptors from PubChem (CID 124190914), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il