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Chemical structure of ONO-5334

GC61158

ONO-5334

Also known as N-[(1S)-3-[(2Z)-2-[(4R)-3,4-dimethyl-1,3-thiazolidin-2-ylidene]hydrazinyl]-1-(oxan-4-yl)-2,3-dioxopropyl]cycloheptanecarboxamide

ONO-5334 is a potent, selective and orally active cathepsin K inhibitor with Ki values of 0·10 nM, 0·049 nM and 0·85 nM for human, rabbit and rat cathepsin K, respectively

ChemicalCAS868273-90-9MW438.58FormulaC21H34N4O4S
CAS number
868273-90-9
Molecular weight
438.58
Formula
C21H34N4O4S
Solubility
DMSO ： 50 mg/mL (114·00 mM; Need ultrasonic)
InChIKey
BTZCSXIUAFVRTE-CHGLIHOBSA-N
Catalogue number
GC61158
Brand
GLPBIO
Computed properties PubChem CID 11582982 · XLogP 3.1 · TPSA 125 Ų · H-bond donors 2
XLogP
3.1
TPSA
125 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
6
Heavy atoms
30

SMILES C[C@@H]1CS/C(=N\NC(=O)C(=O)[C@H](C2CCOCC2)NC(=O)C3CCCCCC3)/N1C

Computed descriptors from PubChem (CID 11582982), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.