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Chemical structure of ONO 6818

GC50225

ONO 6818

Also known as 2-(5-amino-6-oxo-2-phenylpyrimidin-1-yl)-N-[1-(5-tert-butyl-1,3,4-oxadiazol-2-yl)-3-methyl-1-oxobutan-2-yl]acetamide

ONO 6818 (ONO-6818) is a potent and orally active neutrophil elastase inhibitor with a Ki of 12·2 nM

ChemicalCAS208848-19-5MW452.51FormulaC23H28N6O4
CAS number
208848-19-5
Molecular weight
452.51
Formula
C23H28N6O4
Solubility
DMSO ： 100 mg/mL (220·99 mM; Need ultrasonic)
InChIKey
YSIHYROEMJSOAS-UHFFFAOYSA-N
Catalogue number
GC50225
Brand
GLPBIO
Computed properties PubChem CID 216294 · XLogP 2.6 · TPSA 144 Ų · H-bond donors 2
XLogP
2.6
TPSA
144 Ų
H-bond donors
2
H-bond acceptors
8
Rotatable bonds
8
Heavy atoms
33

SMILES CC(C)C(C(=O)C1=NN=C(O1)C(C)(C)C)NC(=O)CN2C(=NC=C(C2=O)N)C3=CC=CC=C3

Computed descriptors from PubChem (CID 216294), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.