GC61061
mGluR2 antagonist 1
Also known as 7-[(2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide
mGluR2 antagonist 1 is a highly potent, orally bioavailable and selective class of mGluR2 negative allosteric modulator (IC50 of 9 nM) with excellent brain permeability
ChemicalCAS1432728-49-8MW377.37FormulaC21H16FN3O3
- CAS number
- 1432728-49-8
- Molecular weight
- 377.37
- Formula
- C21H16FN3O3
- Solubility
- DMSO： 100 mg/mL (264·99 mM)
- InChIKey
- XSTBUOHORFUCIB-UHFFFAOYSA-N
- Catalogue number
- GC61061
- Brand
- GLPBIO
Computed properties PubChem CID 71566598 · XLogP 1.8 · TPSA 93.4 Ų · H-bond donors 1
- XLogP
- 1.8
- TPSA
- 93.4 Ų
- H-bond donors
- 1
- H-bond acceptors
- 5
- Rotatable bonds
- 4
- Heavy atoms
- 28
SMILES C1CC(=O)N(C1=O)CC2=CC3=C(C=C2)C(=CC(=N3)C(=O)N)C4=CC=C(C=C4)F
Computed descriptors from PubChem (CID 71566598), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il