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Chemical structure of LY2140023

GC61016

LY2140023

Also known as (1R,4S,5S,6S)-4-[[(2S)-2-amino-4-methylsulfanylbutanoyl]amino]-2,2-dioxo-2lambda6-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic acid

LY2140023 (LY2140023) is an orally active, methionine prodrug of the selective mGlu2/3 receptor agonist LY404039

ChemicalCAS635318-55-7MW366.41FormulaC12H18N2O7S2
CAS number
635318-55-7
Molecular weight
366.41
Formula
C12H18N2O7S2
Solubility
DMSO: 13·33 mg/mL (36·38 mM); Water: < 0·1 mg/mL (insoluble)
InChIKey
VOYCNOJFAJAILW-CAMHOICYSA-N
Catalogue number
GC61016
Brand
GLPBIO
Computed properties PubChem CID 25195354 · XLogP -4.4 · TPSA 198 Ų · H-bond donors 4
XLogP
-4.4
TPSA
198 Ų
H-bond donors
4
H-bond acceptors
9
Rotatable bonds
7
Heavy atoms
23

SMILES CSCC[C@@H](C(=O)N[C@]1(CS(=O)(=O)[C@@H]2[C@H]1[C@H]2C(=O)O)C(=O)O)N

Computed descriptors from PubChem (CID 25195354), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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