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Chemical structure of LY2157299

GC18015

LY2157299

Also known as 4-[2-(6-methyl-2-pyridinyl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]quinoline-6-carboxamide

LY2157299 is an oral and selective TGF-β receptor type I (TGF-βRI) kinase inhibitor with an IC50 value of 56nM

ChemicalCAS700874-72-2MW369.42FormulaC22H19N5O
CAS number
700874-72-2
Molecular weight
369.42
Formula
C22H19N5O
Solubility
≥ 18·45mg/mL in DMSO
InChIKey
IVRXNBXKWIJUQB-UHFFFAOYSA-N
Catalogue number
GC18015
Brand
GLPBIO
Computed properties PubChem CID 10090485 · XLogP 2.4 · TPSA 86.7 Ų · H-bond donors 1
XLogP
2.4
TPSA
86.7 Ų
H-bond donors
1
H-bond acceptors
4
Rotatable bonds
3
Heavy atoms
28

SMILES CC1=NC(=CC=C1)C2=NN3CCCC3=C2C4=C5C=C(C=CC5=NC=C4)C(=O)N

Computed descriptors from PubChem (CID 10090485), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.