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Chemical structure of Angoline hydrochloride

GC60586

Angoline hydrochloride

Also known as 1,2,13-trimethoxy-12-methyl-13H-[1,3]benzodioxolo[5,6-c]phenanthridine;hydrochloride

Angoline hydrochloride is a potent and selective IL6/STAT3 signaling pathway inhibitor with an IC50 of 11·56 μM· Angoline hydrochloride inhibits STAT3 phosphorylation and its target gene expression, and inhibits cancer cell proliferation

ChemicalCAS1071676-04-4MW415.87FormulaC22H22ClNO5
CAS number
1071676-04-4
Molecular weight
415.87
Formula
C22H22ClNO5
InChIKey
IHTYZEWKBYYBBI-UHFFFAOYSA-N
Catalogue number
GC60586
Brand
GLPBIO
Computed properties PubChem CID 162642249 · TPSA 49.4 Ų · H-bond donors 1 · H-bond acceptors 6
TPSA
49.4 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
3
Heavy atoms
29

SMILES CN1C(C2=C(C=CC(=C2OC)OC)C3=C1C4=CC5=C(C=C4C=C3)OCO5)OC.Cl

Computed descriptors from PubChem (CID 162642249), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Pricing
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Documents
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