GC60585
Angoline
Also known as 1,2,13-trimethoxy-12-methyl-13H-[1,3]benzodioxolo[5,6-c]phenanthridine
Angoline is a potent and selective IL6/STAT3 signaling pathway inhibitor with an IC50 of 11·56 μM· Angoline inhibits STAT3 phosphorylation and its target gene expression, and inhibits cancer cell proliferation
ChemicalCAS21080-31-9MW379.41FormulaC22H21NO5
- CAS number
- 21080-31-9
- Molecular weight
- 379.41
- Formula
- C22H21NO5
- InChIKey
- LVWAKZBZWYHYCJ-UHFFFAOYSA-N
- Catalogue number
- GC60585
- Brand
- GLPBIO
Computed properties PubChem CID 189060 · XLogP 4.2 · TPSA 49.4 Ų · H-bond donors 0
- XLogP
- 4.2
- TPSA
- 49.4 Ų
- H-bond donors
- 0
- H-bond acceptors
- 6
- Rotatable bonds
- 3
- Heavy atoms
- 28
SMILES CN1C(C2=C(C=CC(=C2OC)OC)C3=C1C4=CC5=C(C=C4C=C3)OCO5)OC
Computed descriptors from PubChem (CID 189060), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il