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Chemical structure of ACT-389949

GC60564

ACT-389949

Also known as N-[2-[[4-(1,1-difluoroethyl)-1,3-oxazol-2-yl]methyl]triazol-4-yl]-2-methyl-5-(3-methylphenyl)-1,3-oxazole-4-carboxamide

ACT-389949 is a first-in-class, potent and selective and agonist of formyl peptide receptor type 2 (FPR2)/Lipoxin A4 receptor (ALX), with an EC50 of 3 nM for FPR2/ALX internalization into monocytes

ChemicalCAS1258417-54-7MW428.39FormulaC20H18F2N6O3
CAS number
1258417-54-7
Molecular weight
428.39
Formula
C20H18F2N6O3
Solubility
DMSO： 10 mg/mL (23·34 mM; ultrasonic and adjust pH to 1 with HCl)
InChIKey
PBTWPEDVIMHJEO-UHFFFAOYSA-N
Catalogue number
GC60564
Brand
GLPBIO
Computed properties PubChem CID 49834265 · XLogP 3.5 · TPSA 112 Ų · H-bond donors 1
XLogP
3.5
TPSA
112 Ų
H-bond donors
1
H-bond acceptors
9
Rotatable bonds
6
Heavy atoms
31

SMILES CC1=CC(=CC=C1)C2=C(N=C(O2)C)C(=O)NC3=NN(N=C3)CC4=NC(=CO4)C(C)(F)F

Computed descriptors from PubChem (CID 49834265), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.