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Chemical structure of ACT-132577

GC13236

ACT-132577

Also known as 5-(4-bromophenyl)-4-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-6-(sulfamoylamino)pyrimidine

ACT-132577 (ACT-132577) is the major and pharmacologically active metabolite of Macitentan

ChemicalCAS1103522-45-7MW546.19FormulaC16H14Br2N6O4S
CAS number
1103522-45-7
Molecular weight
546.19
Formula
C16H14Br2N6O4S
Solubility
DMSO ： 25 mg/mL (45·77 mM; ultrasonic and warming and heat to 60°C)
InChIKey
DKULOVKANLVDEA-UHFFFAOYSA-N
Catalogue number
GC13236
Brand
GLPBIO
Computed properties PubChem CID 25099191 · XLogP 2.4 · TPSA 151 Ų · H-bond donors 2
XLogP
2.4
TPSA
151 Ų
H-bond donors
2
H-bond acceptors
10
Rotatable bonds
8
Heavy atoms
29

SMILES C1=CC(=CC=C1C2=C(N=CN=C2OCCOC3=NC=C(C=N3)Br)NS(=O)(=O)N)Br

Computed descriptors from PubChem (CID 25099191), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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